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(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide

α-Amyloid Precursor Protein Modulator

CAS: 497259-23-1

Molecular Formula: C27H30F3N3O3

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  5. (2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide

(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide - Names and Identifiers

Name α-Amyloid Precursor Protein Modulator
Synonyms TPPB
α-Amyloid Precursor Protein Modulator
alpha-AMyloid Precursor Protein Modulator
(2E,4E)-N-((2S,5S)-5-(hydroxymethyl)-2-isopropyl-1-methyl-3-oxo-1,2,3,4,5,6-hexahydrobenzo[e][1,4]diazocin-8-yl)-5-(4-(trifluoromethyl)phenyl)penta-2,4-dienamide
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
CAS 497259-23-1
EINECS 230-025-4

(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide - Physico-chemical Properties

Molecular FormulaC27H30F3N3O3
Molar Mass501.5406096
Density1.229
Boling Point728.8±60.0 °C
pKa12.76±0.60(Predicted)
Storage ConditionRoom Temprature
UseIntroduction TPPB is a benzo-lactam-derived, cell-permeable protein kinase C (PKC) activator with a Ki value of 11.9 nM.
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
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MedChemExpress (MCE)
Spot supply
Product Name: TPPB Visit Supplier Webpage Request for quotation
CAS: 497259-23-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: TPPB Visit Supplier Webpage Request for quotation
CAS: 497259-23-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: TPPB  Visit Supplier Webpage Request for quotation
CAS: 497259-23-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: TPPB Visit Supplier Webpage Request for quotation
CAS: 497259-23-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
5-Chloroimidazo[1,2-A]Pyridine-3-Carbaldehyde
4H-Thieno[2',3':4,5]pyrimido[2,1-b]benzoxazol-4-one, 2-phenyl-
331235-76-8
3-HYDROXY-N-METHYLPIPERIDINE
(1R)-1-Methyl-4α-[(S)-1,2,2-trimethylcyclopentane-1β-yl]-2-cyclohexene-1β-ol
2,5-dichloro-N-(4-methylbenzo[d]thiazol-2-yl)benzamide
2-{4-[(3,4-dichlorobenzyl)oxy]-3-ethoxyphenyl}-3-(4-ethylphenyl)-2,3-dihydro-4(1H)-quinazolinone
1,4-Benzodioxin-6-carboxamide, N-[3-(5-chloro-2-benzoxazolyl)phenyl]-2,3-dihydro-
3,8''-Biapigenin
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